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Category: 5. Biology
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Challenging Decades of Neuroscience: Brain Cells Are More Plastic Than Previously Thought
Using in-vitro models of a specific type of brain cell, scientists have demonstrated that neurons can transform from one type to another. Neurons are specialized brain cells responsible for transmitting signals throughout the body. For a long…
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Exercise Reduces Effects of Mental Fatigue in Older Adults
Regular exercise may reduce the cognitive and physical effects of mental fatigue in older adults. The corresponding study was published in the Journal of Aging and Physical Activity.
“This study shows how…
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Cerium oxide nanoparticles alleviate drought stress in apple seedlings by regulating ion homeostasis, antioxidant defense, gene expression, and phytohormone balance
Chlorophyll fluorescence
Based on the results, the highest amount of Fm was observed in the control and the treatment of 100 mg/L CeO2 NPs at the no stress level, and the lowest amount was observed in CeO2 NPs treatment at the stress level of 25%…
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A structural and mechanistic model for BSEP dysfunction in PFIC2 cholestatic disease
Thermal stability of BSEP patient variants
BSEP variants drive PFIC2 disease through decreased BSEP expression and function. Our study aimed to determine if protein thermodynamic stability is linked to protein trafficking defects and diminished…
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The single-cell spatial landscape of stage III colorectal cancers
A computational framework for analyzing single-cell spatial features in CRC cancer
We performed IMC assays on a set of stage III CRC samples to achieve high-resolution, single-cell spatial profiling (Fig. 1a). The IMC multiplexed panel utilized 16…
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Intergenerational metabolic effects of cold exposure
Intergenerational metabolic effects of cold exposure
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From CRISPR screens to circuits: identifying key regulators in T cell activation and state transitions
A recent study published in Nature by Maya M. Arce and colleagues unveils the role of central gene circuits in governing the delicate balance between T cell rest and T cell activation.1 This work…
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Deciphering cancer complexity: perspective on hematopoietic remodeling-mediated immunosuppression
Hanahan D, Weinberg R. The hallmarks of cancer. Cell. 2000;100:57–70.
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Binnewies M, Roberts EW, Kersten K, Chan V, Fearon DF, Merad M, et al. Understanding the tumor immune…
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The genetic basis of human height
Tanner, J. M. A History of the Study of Human Growth (Cambridge Univ. Press, 1981).
Galton, F. Regression towards mediocrity in hereditary stature. J. R. Anthropol. Inst. 5, 329–348 (1885).
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