University of Staffordshire, Department of Sports and Science, School of Health, Education, Policing and Sciences, Science Centre, Leek Road, Stoke-on-Trent, ST4 2DF, UK
Rebecca H. Finch, Geraldine Vitry & Willian A. da Silveira
International…
Category: 5. Biology
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p53 transcriptionally activates DCP1B to suppress tumor progression and enhance tumor sensitivity to PI3K blockade in non-small cell lung cancer
Reagents, antibodies, and plasmids
Nutlin-3, 5-fluorouracil (5-Fu), Cisplatin, Etoposide, APG-115, Alpelisib, Actinomycin D (Act.D), and Dimethyl sulfoxide (DMSO) were purchased from MedChemExpress (MCE, Shanghai, China). Other reagents and kits,…
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CRISPR–Csm guided RNA imaging | Nature Methods
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Conservation priority corridors enhance the effectiveness of protected area networks in China
Jones, K. R. et al. One-third of global protected land is under intense human pressure. Science 360, 788–791 (2018).
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Terraube, J., Van Doninck, J., Helle, P. & Cabeza,…
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Like TIRs in rain | Nature Plants
The canonical auxin pathway in the Arabidopsis nucleus was characterized two decades ago: auxin acts as a molecular glue to bind the TIR1 F-box auxin receptor (and five AFB homologues) to small auxin and indole-3-acetic acid (Aux/IAA) proteins….
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Tertiary lymphoid structures associated with improved survival and enhanced antitumor immunity in acral melanoma
Paijens, S. T., Vledder, A., de Bruyn, M. & Nijman, H. W. Tumor-infiltrating lymphocytes in the immunotherapy era. Cell. Mol. Immunol. 18, 842–859 (2021).
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Understanding protein subcellular compartmentalization signals
Groups of proteins with shared function selectively localize to specific subcellular compartments and assemble to perform their roles. These assemblies, described with a variety of names such as condensates, aggregates, puncta, hubs and…
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RBM24 regulates apoptosis rates by modulating global transcriptome profile in CAL27 cells
In vitro functional analysis of RBM24 in CAL27 cells
It has been shown that RBM24 can be one of the biomarkers for the prognostic assessment of OSCC. To determine the detailed mechanism of RBM24 in OSCC, we constructed and tested a model of RBM24…
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UPRmt controls the mesenchymal-to-epithelial transition
UPRmt controls the mesenchymal-to-epithelial transition
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Generation of induced alveolar assembloids with functional alveolar-like macrophages
Human pluripotent stem cells (hPSCs)
In this study, one hESC lines (H9) and one hiPSC (CRLe2-iPSC) were used. hESCs (H9) were obtained from the WiCell Research Institute (Wicell, Madison, WI) and hiPSC were reprogrammed from skin fibroblast (ATCC,…
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