A new functionalized fluorosensor detects enteroviral RNA with high sensitivity in real time. It marks a major step in safer, more effective viral diagnostics. In a notable breakthrough, researchers at the Nanoscience Center (NSC) of the…
Category: 5. Biology
-
Next-Gen Fluorosensor Detects Viral RNA in Real Time
-
Serum Klotho levels and epilepsy among U.S. adults in the NHANES 2013–2016: a cross-sectional study
Sen, A., Jette, N., Husain, M. & Sander, J. W. Epilepsy in older people. Lancet (London, England) 395(10225), 735–748. https://doi.org/10.1016/s0140-6736(19)33064-8 (2020).
Google Scholar
…Continue Reading
-
How reducing oxygen-transport may lower the risk of developing Parkinson’s disease
Rose, K. N., Schwarzschild, M. A. & Gomperts, S. N. Clearing the smoke: what protects smokers from Parkinson’s disease. Mov. Disord. Off. J. Mov. Disord. Soc. 39, 267–272 (2024).
Google Scholar
…Continue Reading
-
Role of phospholipase Cη1 in lateral habenula astrocytes in depressive-like behavior in mice
Animals
To generate Plch1f/f mice, we used the KOMP ES cell line Plch1tm1a(KOMP)Wtsi (RRID: MMRRC_060360-UCD) from the Mutant Mouse Resource and Research Center at the University of California at Davis, an National Institutes of Health…
Continue Reading
-
Unravelling the conundrum of nucleolar NR2F1 localization using antibody-based approaches in vitro and in vivo
Stadler, C., Skogs, M., Brismar, H., Uhlén, M. & Lundberg, E. A single fixation protocol for proteome-wide immunofluorescence localization studies. J. Proteom. 73, 1067–1078 (2010).
Google Scholar
…Continue Reading
-
Relationship between optical properties and internal quality of Orah Mandarins during storage
System validation results
The detection accuracy of the SIS system is verified by measuring the optical properties of water, as shown in Fig. 3. In the range of 400 ~ 1050 nm, there is a significant O-H bond absorption peak at 980 nm for…
Continue Reading
-
Monocyte-macrophage membrane expression of IL-1R2 is a severity biomarker in sepsis
Characteristics of the population
Patients analyzed in the present study were part of a population of 178 subjects admitted to Humanitas Research Hospital [12]. In this cohort, a total of 117 patients were analyzed based on the availability of…
Continue Reading
-
Bilayer sol-gel system for local prevention in prosthetic joint infections and osteointegration improvement
Preparation of the inner layer formulation
For inner layer biofunctionalisation, dipyridamole was chosen.
The osteoinductive layer coating was prepared by sol–gel technology. Methyl-trimethoxysilane (MTMOS, 95%, Sigma Aldrich, St. Louis, MI, USA)…
Continue Reading
-
The triage role of cytological DNA methylation in women with non-16/18, specifically genotyping high-risk HPV infection
Characteristics of the participants
As shown in Fig. 1, a total of 1307 women with non-16/18 hrHPV(+) were included in this study. The characteristics of the participants are summarised in Table 1. In total, 643 women had cervical histology…
Continue Reading
-
Structural and dynamic features of cagrilintide binding to calcitonin and amylin receptors
Structure determination
Human CTR, plus or minus individual RAMPs, and a stabilised form of Gαs (dominant negative Gs (DNGs)) and Gβ1γ2, were co-expressed in Trichoplusia ni insect cells. The assembly of complexes with Gs protein was stimulated…
Continue Reading