The researchers sequenced a panel of 226 citrus accessions including sour oranges, landraces and cultivated citrus, and integrated published genomes of sweet orange, pummelo and mandarin in their analyses. Unlike sweet oranges, sour oranges…
Category: 5. Biology
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Novel derivatives of brincidofovir and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine inhibit orthopoxviruses and human adenoviruses more potently than brincidofovir
Petersen, B. W., Karem, K. L. & Damon, I. K. in Viral Infections of Humans, (eds Kaslow, R., Stanberry, L., & Le Duc, J.) 501-517 (Springer, 2014).
Singh, P. et al. The resurgence of monkeypox: epidemiology, clinical features, and public health…
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The art of war: burning stores to fuel anti-viral immunity
Krapić, M. et al. Nat. Metab. https://doi.org/10.1038/s42255-025-01273-2 (2025).
Willmann, K. & Moita, L. F. Cell Metab. 36, 927–946 (2024).
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Palmer, C. S. Nat. Metab.…
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Genetic modulation of rare earth nanoparticle biotransformation shapes biological outcomes
Materials
We acquired a library of metal oxide (MOx) nanoparticles (NPs) through in-house synthesis37,38 or from US-Nano (Houston, TX, USA). Phagolysosomal simulated fluid (PSF; 142 mg/L Na2HPO4, 6.65 g/L NaCl, 62 mg/L Na2SO4, 29 mg/L CaCl2…
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Longitudinal voice monitoring in a decentralized Bring Your Own Device trial for respiratory illness detection
Trial design
The AcRIS study was a low-interventional, observational trial, with the primary objective of characterizing the relationship between symptoms and voice features for individuals with acute viral respiratory illness caused by…
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Peripheral neural stem cells from the neural tube contribute to multi-organ neurogenesis
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Han, D. et al. Multipotent neural stem cells originating from neuroepithelium exist…
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Balance between bile acid conjugation and hydrolysis activity can alter outcomes of gut inflammation
Animals
All animal procedures were approved by the Michigan State University Institutional Animal Care and Use Committee and conformed to NIH guidelines. Mice were housed in a temperature and humidity-controlled room under a 12-h cycle of light…
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Relationship between psychological resilience and quality of life in cancer patients and the multiple mediating roles of stigma and self perceived burden
Belcher, S. M. et al. Financial hardship and quality of life among patients with advanced cancer receiving outpatient palliative care: A pilot study. Cancer Nurs. 46(1), 3–13 (2023).
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Glycogen stores mediated by the p53-GYS1 feedback circuit engenders platinum resistance in ovarian clear cell carcinoma
Lheureux S, Braunstein M, Oza AM. Epithelial ovarian cancer: Evolution of management in the era of precision medicine. CA Cancer J Clin. 2019;69:280–304.
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Single cell transcriptome sequencing indicates the cellular heterogeneity of small intestine tissue in celiac disease
Single cell transcriptomic analysis identifies the spectrum of cell populations in the small intestinal tissue of patients with CeD
To investigate the diverse cellular components within the small intestinal tissues of patients with CeD, we used…
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