Category: 5. Biology

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  • Study of coronavirus diversity in wildlife in Northern Cambodia suggests continuous circulation of SARS-CoV-2-related viruses in bats

    Study of coronavirus diversity in wildlife in Northern Cambodia suggests continuous circulation of SARS-CoV-2-related viruses in bats

  • Zhou, P. et al. A pneumonia outbreak associated with a new coronavirus of probable Bat origin. Nature 579 (7798), 270–273 (2020).

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  • Music therapy as a preventive intervention for postpartum depression: modulation of synaptic plasticity, oxidative stress, and inflammation in a mouse model

    Music therapy as a preventive intervention for postpartum depression: modulation of synaptic plasticity, oxidative stress, and inflammation in a mouse model

    Animal preparation

    Female BALB/c mice, aged 11 weeks and weighing 22 ± 1.5 g, were acquired from the Fang Yuanyuan Breeding Farm, located in Beijing, China. These animals were housed under controlled environmental conditions, maintaining a…

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  • YTHDC1 phase separation drives the nuclear export of m6A-modified lncNONMMUT062668.2 through the transport complex SRSF3–ALYREF–XPO5 to aggravate pulmonary fibrosis

    YTHDC1 phase separation drives the nuclear export of m6A-modified lncNONMMUT062668.2 through the transport complex SRSF3–ALYREF–XPO5 to aggravate pulmonary fibrosis

    All animal experiments followed the guidelines and protocols approved by the Research Ethics Committee of Affiliated Hospital, Binzhou Medical university. the Research Ethics Committee of Affiliated Hospital approved the use of human samples and…

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  • Cytoskeletal alterations in neuronal cells implicate Toxoplasma gondii secretory machinery and host microRNA-containing extracellular vesicles

    Cytoskeletal alterations in neuronal cells implicate Toxoplasma gondii secretory machinery and host microRNA-containing extracellular vesicles

    Ethical approval

    The Regional Animal Research Ethical Board, Stockholm, Sweden, approved experimental procedures and protocols involving extraction of cells from mice (permit number 16403-2022), following proceedings described in EU legislation…

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  • Comparative in vitro immunoreactivity and protein analysis of Trimeresurus albolabris and Tropidolaemus wagleri venoms

    Comparative in vitro immunoreactivity and protein analysis of Trimeresurus albolabris and Tropidolaemus wagleri venoms

  • Gutierrez, J. M. et al. Snakebite envenoming. Nat. Rev. Dis. Primers 3, 17063. https://doi.org/10.1038/nrdp.2017.63 (2017).

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  • Vanuopadath, M., Shaji, S. K., Raveendran,…

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  • The clinical value of metagenomic next-generation sequencing in the diagnosis of pulmonary tuberculosis and the exploration of lung microbiota characteristics

    The clinical value of metagenomic next-generation sequencing in the diagnosis of pulmonary tuberculosis and the exploration of lung microbiota characteristics

    PTB is a significant infectious disease that poses a severe threat to the health of people globally. The heterogeneity of PTB infection, onset, and treatment, aside from differences in individual genetic background, the resident microbial flora…

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  • Effect of neurohormonal therapeutic in left ventricle global and regional function in Chagas cardiomyopathy in a translational animal experimental model

    Effect of neurohormonal therapeutic in left ventricle global and regional function in Chagas cardiomyopathy in a translational animal experimental model

    The experimental animal model of CD in Syrian hamsters simulates CCC with the same characteristics as human disease. Left ventricle remodeling and myocardial dysfunction can be assessed by echocardiography dedicated to small animal models,…

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  • Design, synthesis and optimization of TarO inhibitors as multifunctional antibiotics against Methicillin-resistant Staphylococcus aureus

    Design, synthesis and optimization of TarO inhibitors as multifunctional antibiotics against Methicillin-resistant Staphylococcus aureus

    General procedure for synthesis of compounds 1–7

    To a 25 mL two-necked flask equipped with a magnetic stirrer was added 31a (0.5 mmol, l.0 equiv). The flask was then placed at -78 °C and 5 mL anhydrous THF was added under nitrogen….

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