Frailty is a complex age-related clinical syndrome characterized by a progressive decline in functioning across multiple physiological systems, with consequent increased vulnerability to stressors and high risk of hospitalization and mortality1….
Category: 5. Biology
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Refining microbiome diversity analysis by concatenating and integrating dual 16S rRNA amplicon reads
Comparative validation of concatenation and merging methods for gut microbiome analysis
Our research assessed the effectiveness of concatenating versus merging pair-end reads across various 16S rRNA regions, using the ZIEL-II mock community…
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Mutant CEBPA promotes tolerance to inflammatory stress through deficient AP-1 activation
The p30 isoform is associated with decreased inflammatory gene expression
To define the transcriptional impact of p30 and p42 isoforms on HSPCs, we first used the mouse hematopoietic progenitor cell line HPC-745. HPC-7 cells recapitulate the…
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triangulaR: an R package for identifying AIMs and building triangle plots using SNP data from hybrid zones
Here, we present triangulaR (https://github.com/omys-omics/triangulaR), an R package for identifying AIMs, calculating hybrid index and interclass heterozygosity, and visualizing triangle plots from SNP data. To facilitate use of triangulaR and…
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Mutualism breakdown underpins evolutionary rescue in an obligate cross-feeding bacterial consortium
Bell, G. Evolutionary rescue. Annu. Rev. Ecol. Evol. Syst. 48, 605–627 (2017).
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Diniz-Filho, J. A. F. & Bini, L. M. Will life find a way out? evolutionary rescue and Darwinian…
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Particulate matter and co-occurring genetic risk induce oxidative stress and cardiac and brain Alzheimer’s pathology
Numerical source data for all graphs in the manuscript can be found in the supplementary data 1 file.
Mice exposure survival
No differences in survival were noticed across male groups during PM2.5 exposure, whereas three female AD mice exposed to…
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Cortico force coherence of the finger and toe with slight rhythmic pressure on force sensors using electroencephalography
Participants
Fourteen healthy volunteers (all men; age range, 20–23 years; mean age, 21.1 years) were examined. All participants were right-handed and right-footed, as determined by the Edinburgh Handedness Inventory27 and the Waterloo…
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Genomes of Prochlorococcus, Synechococcus, bacteria, and viruses recovered from marine picocyanobacteria cultures based on Illumina and Qitan nanopore sequencing
Cesar-Ribeiro, C., Barbosa, C. S., Terra, V. & Ghisi, N. D. C. Prochlorococcus and Synechococcus marine cyanobacteria: a scientometrics review. Lat Am J Aquat Res. 51, 556–569 (2023).
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Study of coronavirus diversity in wildlife in Northern Cambodia suggests continuous circulation of SARS-CoV-2-related viruses in bats
Zhou, P. et al. A pneumonia outbreak associated with a new coronavirus of probable Bat origin. Nature 579 (7798), 270–273 (2020).
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Music therapy as a preventive intervention for postpartum depression: modulation of synaptic plasticity, oxidative stress, and inflammation in a mouse model
Animal preparation
Female BALB/c mice, aged 11 weeks and weighing 22 ± 1.5 g, were acquired from the Fang Yuanyuan Breeding Farm, located in Beijing, China. These animals were housed under controlled environmental conditions, maintaining a…
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