Category: 5. Biology

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  • Anti-T lymphocyte globulin plus posttransplant cyclophosphamide 25 mg/kg versus posttransplant cyclophosphamide 50 mg/kg in patients with acute leukemias

    Anti-T lymphocyte globulin plus posttransplant cyclophosphamide 25 mg/kg versus posttransplant cyclophosphamide 50 mg/kg in patients with acute leukemias

    Subjects

    We conducted this multicenter retrospective non-randomized study and analyzed 70 patients who received their first transplantation for acute leukemias in their first remission and had PTCy dosing of 25 mg/kg x2 plus ATLG (ATLG+PTCy25,…

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  • Climate change impacts on altitudinal movements of society large mammals in the Alborz

    Climate change impacts on altitudinal movements of society large mammals in the Alborz

  • Abrahms, B. et al. Emerging perspectives on resource tracking and animal movement ecology. Trends Ecol. Evol. 36(4), 308–320 (2021).

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  • Florko, K. R. et al. Linking…

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  • TMEM160 inhibits KEAP1 to suppress ferroptosis and induce chemoresistance in gastric cancer

    TMEM160 inhibits KEAP1 to suppress ferroptosis and induce chemoresistance in gastric cancer

    Patient samples and clinical data collection

    Paraffin-embedded tissue samples were collected from 180 patients with GC who underwent surgical treatment without any systemic or local therapy from January 2017 to April 2019 and 89 patients with…

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  • FLT1-enriched extracellular vesicles induce a positive feedback loop between nasopharyngeal carcinoma cells and endothelial cells to promote angiogenesis and tumour metastasis

    FLT1-enriched extracellular vesicles induce a positive feedback loop between nasopharyngeal carcinoma cells and endothelial cells to promote angiogenesis and tumour metastasis

  • Sang Y, Cheng C, Zeng YX, Kang TB. Snail promotes metastasis of nasopharyngeal carcinoma partly by down-regulating TEL2. Cancer Commun. 2018;38:58.

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  • Hu Q, Lin X, Ding L, Zeng Y, Pang…

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  • The impact of psychological capital on job performance among government employees in China

    The impact of psychological capital on job performance among government employees in China

    Basic questionnaire information

    This survey involved a total of 2,357 government employees, with males accounting for 44.1% and females accounting for 55.9%, indicating a slightly higher participation rate among females, as shown in Table 1. In…

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  • Genome-wide identification of the TGF-β superfamily and their expression in the Chinese mitten crab Eriocheir sinensis

    Genome-wide identification of the TGF-β superfamily and their expression in the Chinese mitten crab Eriocheir sinensis

  • Cui, Z. X. et al. The Chinese mitten crab genome provides insights into adaptive plasticity and developmental regulation. Nat. Commun. https://doi.org/10.1038/s41467-021-22604-3 (2021).

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    PubMed Central 

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  • Gene expression profile of anoikis reveals new subtypes of liver cancer and discovery of therapeutic targets and biomarkers

    Gene expression profile of anoikis reveals new subtypes of liver cancer and discovery of therapeutic targets and biomarkers

    The development of liver cancer is closely related to Anoikis

    We obtained the RNA-seq data of patients with liver cancer and normal controls in TCGA database, and analyzed the mutation load and difference of anoikis-related genes. We found that…

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  • Type I collagen secreted in white matter lesions inhibits remyelination and functional recovery

    Type I collagen secreted in white matter lesions inhibits remyelination and functional recovery

    Human brain samples

    We obtained paraffin sections from postmortem brain samples of stroke patients and biopsied brain samples of MS patients from the National Center of Neurology and Psychiatry (NCNP) or Brain Research Institute at Niigata…

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  • Acetylcholine muscarinic M2 receptor maintains human Schwann-like adipose-derived phenotype in the absence of differentiating medium

    Acetylcholine muscarinic M2 receptor maintains human Schwann-like adipose-derived phenotype in the absence of differentiating medium

    Human adipose-derived stem cell harvesting and culture

    Human subcutaneous abdominal adipose tissue was withdrawn from 7 consenting patients undergoing reconstructive surgery at Wythenshawe Hospital, Manchester University NHS Foundation Trust, UK….

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