Category: 5. Biology

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  • Curcumin reduces pain after spinal cord injury in rats by decreasing oxidative stress and increasing GABAA receptor and GAD65 levels

    Curcumin reduces pain after spinal cord injury in rats by decreasing oxidative stress and increasing GABAA receptor and GAD65 levels

  • Kim, H. Y. et al. Prevalence and characteristics of neuropathic pain in patients with spinal cord injury referred to a rehabilitation center. Annals Rehabilitation Med. 44 (6), 438–449 (2020).

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  • Author Correction: Viscoelastic synthetic antigen-presenting cells for augmenting the potency of cancer therapies

    Author Correction: Viscoelastic synthetic antigen-presenting cells for augmenting the potency of cancer therapies

  • These authors contributed equally: Zeyang Liu, Yan-Ruide Li, Youcheng Yang.

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  • Bacterial biofilm-derived H-NS protein acts as a defense against Neutrophil Extracellular Traps (NETs)

    Bacterial biofilm-derived H-NS protein acts as a defense against Neutrophil Extracellular Traps (NETs)

  • Penesyan, A., Paulsen, I. T., Kjelleberg, S. & Gillings, M. R. Three faces of biofilms: a microbial lifestyle, a nascent multicellular organism, and an incubator for diversity. NPJ Biofilms Microbiomes 7, 80 (2021).

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  • Inhibitory effects of benzyl isothiocyanate on widespread mcr-1-harbouring IncX4 plasmid transfer

    Inhibitory effects of benzyl isothiocyanate on widespread mcr-1-harbouring IncX4 plasmid transfer

    Antimicrobial resistance (AMR): frequency and mechanism

    The antimicrobial susceptibility testing revealed that 133 E. coli and 188 K. pneumoniae clinical isolates exhibited MDR phenotype and resistance to at least one drug in the ESCs category….

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  • DNMT1 is required for efficient DSB repair and maintenance of replication fork stability, and its loss reverses resistance to PARP inhibitors in cancer cells

    DNMT1 is required for efficient DSB repair and maintenance of replication fork stability, and its loss reverses resistance to PARP inhibitors in cancer cells

  • Ceccaldi R, Rondinelli B, D’Andrea AD. Repair pathway choices and consequences at the double-strand break. Trends Cell Biol. 2016;26:52–64.

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  • Cruz-Garcia A, Lopez-Saavedra A, Huertas…

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  • The role of land use in terrestrial support of boreal lake food webs

    The role of land use in terrestrial support of boreal lake food webs

    Permissions for sample collection and ethical matters

    Finnish Everyone’s Rights, fishing permits from local fishery boards and Finnish Centre for Economic Development, Transport and the Environment (e.g. POSELY: 1271/5712/2012, please see full…

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  • Lysosomal lipid peroxidation contributes to ferroptosis induction via lysosomal membrane permeabilization

    Lysosomal lipid peroxidation contributes to ferroptosis induction via lysosomal membrane permeabilization

    Ethical statement

    This research complies with all relevant ethical regulations. All procedures and animal care were approved by the Committee on Ethics of Animal Experiments, Graduate School of Pharmaceutical Sciences, Kyushu University, and…

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  • An optimized luciferin formulation for NanoLuc-based in vivo bioluminescence imaging

    An optimized luciferin formulation for NanoLuc-based in vivo bioluminescence imaging

    CFz9 with improved solubility for in vivo BLI applications

    CFz (Fig. 1a) was previously developed as an improved NanoLuc substrate for non-invasive imaging in animal brains16. For repeated, longitudinal BLI applications, a standard dose of 1.3…

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  • Reward integration in prefrontal-cortical and ventral-hippocampal nucleus accumbens inputs cooperatively modulates engagement

    Reward integration in prefrontal-cortical and ventral-hippocampal nucleus accumbens inputs cooperatively modulates engagement

    mPFC-NAc and vHip-NAc similarly encode outcomes in a probabilistically rewarded environment

    To assess redundancy versus specificity in outcome encoding in two distinct circuits under matched conditions and trial histories, we injected retrograding…

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