Bai, X., Huo, H. & Liu, J. Analysis of mechanical characteristics of walking and running foot functional units based on non-negative matrix factorization. Front. Bioeng. Biotechnol. 11, 1201421 (2023).
Category: 5. Biology
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De novo virulence feature discovery and risk assessment in Klebsiella pneumoniae based on microbial genome vectorization
Our bacterial virulence prediction pipeline methodology is depicted in Fig. 1. The compute environment consisted of a single bare metal machine having 56 Intel(R) Xeon(R) CPU E5-2690 v4 @ 2.60GHz, 250 GB RAM, and running Ubuntu 20.04. Python…
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A neural circuit for sex-dependent conditioned pain hypersensitivity in mice
Animals
The experiments used adult (8–12 weeks) C57BL/6J (Charles River), VgluT2-Cre (Jackson Labs, 028863), Vgat-Cre (Jackson Labs, 028862), and Ai14 (RCL-tdT) (Jackson Labs, 007914) lines of both sexes. The VgluT2-Cre and Vgat-Cre were crossed…
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Workplace flow among clinical residents and professors
Before delving into the broader implications of our findings, it’s important to contextualize them within the psychometric properties of the WOLF as observed in this study. Our confirmatory factor analysis confirmed the original three-factor…
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The subcortical maternal complex safeguards mouse oocyte-to-embryo transition by preventing nuclear entry of SPIN1
Li, L., Lu, X. & Dean, J. The maternal to zygotic transition in mammals. Mol. Asp. Med. 34, 919–938 (2013).
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Li, L., Zheng, P. & Dean, J. Maternal control of early mouse…
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An oncohistone-driven H3.3K27M/CREB5/ID1 axis maintains the stemness and malignancy of diffuse intrinsic pontine glioma
ID1 functions as an oncogenic factor by promoting proliferation and stemness in H3K27M DIPG
ID1 often endows cancer cells with stemness and malignancy hijacked from normal stem cells43,44 and its high expression in DIPG patients has a reduced…
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Dissociation for living | Nature Chemical Biology
N6-methyladenosine (m6A) is one of the most abundant RNA modifications and has an important role in many biological processes. The major writer for m6A is the METTL3–METTL14 complex, whereby METTL3 acts as the catalytic methyltransferase while…
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Benchmarking mouse contamination removing protocols in patient-derived xenografts genomic profiling
Impact of mouse read contamination on PDX transcriptomic data
To examine the impact of mouse read contamination on gene expression, we first compared gene expression values with and without removing mouse reads. For simplicity, we call a sample…
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Microbes in Brooklyn Superfund site teach lessons on fighting industrial pollution
Using advanced DNA sequence analysis, a research team led by NYU Tandon School of Engineering’s Assistant Professor Elizabeth Hénaff has discovered that tiny organisms in Brooklyn’s highly contaminated Gowanus Canal have developed a…
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