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Category: 5. Biology
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IGF2BP3/ESM1/KLF10/BECN1 positive feedback loop: a novel therapeutic target in ovarian cancer via lipid metabolism reprogramming
ESM1 silencing reduced cholesterol synthesis and promoted lipolysis in OC cells
Studies have shown that dysregulation of lipid metabolism affects the development of OC [35, 37]. Our previous work found that ESM1 was related to lipid metabolism [
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Deep learning and sentence embeddings for detection of clickbait news from online content
In this section, discuss research methodology for the detection of news clickbait in Urdu news headlines using ML and DL models. This research methodology consists of four stages including data collection, data preprocessing, and feature…
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Sweetening ferroptosis spread | Nature Chemical Biology
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Galectin-13 reduces membrane localization of SLC7A11 for ferroptosis propagation
Dixon, S. J. et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 149, 1060–1072 (2012).
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In silico prohormone processing | Nature Chemical Biology
Peptide hormones are processed from larger proteins by endopeptidases and have diverse biological functions. For example, glucagon-like peptide-1 (GLP-1) is well known for regulating blood glucose levels and has been used to treat diabetes and…
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Fractional modeling and numerical investigations of COVID-19 epidemic model with non-singular fractional derivatives: a case study
The existence and uniqueness of the fractional-order mathematical model have been recently investigated by researchers31,32,33,34,35,36. In this context, we denote the Banach space as G(M), where \(M =[0,b]\), encompassing real-valued continuous…
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An exceptionally photostable mScarlet3 mutant
An exceptionally photostable mScarlet3 mutant
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The global determinants of climate niche breadth in birds
We begin our analyses by leveraging the highest quality breeding range maps available for birds, inferred with state-of-the-art species distribution models and powered by millions of curated citizen science eBird sightings12,13. At the time of…
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