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This is a summary of: van Olst, L. et al. Microglial mechanisms drive amyloid-β clearance in immunized…
Category: 5. Biology
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Mind over microbiota: neurons call the shots in the gut
Mind over microbiota: neurons call the shots in the gut
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The mechanochemical cycle of reactive full-length human dynein 1
King, S. M. The dynein microtubule motor. Biochim. Biophys. Acta 1496, 60–75 (2000).
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Reck-Peterson, S. L., Redwine, W. B., Vale, R. D. & Carter, A. P. The…
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Computer aided study on cyclic tetrapeptide based ligands as potential inhibitors of Proplasmepsin IV
Calculated descriptors from optimized molecules
Frontier molecular orbital (highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO)) have been reported by several scientists to give accurate qualitative information…
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A novel approach in using insect-based spinach-food waste for gene targeting to cancer tissues
Preparation and characterization of the NPs
NMR analysis of copolymers (SM, HS, PEG- Folic acid) and Characterization of Fe3O4 (NPs) extracted from MSFW
In a first step, the structural components of spermine, hyperbranched spermine (HS), and…
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Real-space heterogeneous reconstruction, refinement, and disentanglement of CryoEM conformational states with HetSIREN
This section starts with a general presentation of the image formation model in CryoEM and then details the architecture of the HetSIREN network and training strategies.
In addition, Supplementary Table 1 summarizes the performance analysis of…
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Detection of viral sequences at single-cell resolution identifies novel viruses associated with host gene expression changes
Anthony, S. J. et al. A strategy to estimate unknown viral diversity in mammals. MBio 4, e00598-13 (2013).
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Jones, K. E. et al. Global trends in…
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A single amino acid mutation alters multiple neutralization epitopes in the respiratory syncytial virus fusion glycoprotein
Cell culture
Henrietta Lack’s (HeLa) cells from American Type Culture Collection (ATCC, CCL2) were grown in Dulbecco’s modified Eagle’s medium (DMEM) containing L-glutamine, glucose, and sodium pyruvate with 10% heat-inactivated fetal bovine…
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Endothelium calls macrophages for destruction
Endothelium calls macrophages for destruction
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Enzymes in secondary pharmacology screening panels: is there room for improvement?
Brennan, R. J. et al. The state of the art in secondary pharmacology and its impact on the safety of new medicines. Nat. Rev. Drug Discov. 23, 525–545 (2024).
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