Category: 5. Biology

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  • GABA and astrocytic cholesterol determine the lipid environment of GABAAR in cultured cortical neurons

    GABA and astrocytic cholesterol determine the lipid environment of GABAAR in cultured cortical neurons

    Spatial Patterning of GABAAR and GM1 lipids in primary neurons through two-color dSTORM

    To determine the spatial relationship of GABAAR relative to GM1 lipid clusters, we employed two-color direct stochastic optical reconstruction microscopy…

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  • Exploring the mechanisms of Chaige Kangyi Recipe in treating recurrent pregnancy loss with insulin resistance

    Exploring the mechanisms of Chaige Kangyi Recipe in treating recurrent pregnancy loss with insulin resistance

  • Dimitriadis, E. et al. Recurrent pregnancy loss. Nat. Rev. Dis. Primers 6 (1), 98 (2020).

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  • Bae, J. H. et al. Future risk of metabolic syndrome after recurrent pregnancy loss: A…

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  • Deep learning based adaptive and automatic measurement of palpebral margin in eyelid morphology

    Deep learning based adaptive and automatic measurement of palpebral margin in eyelid morphology

    Due to the retrospective nature of the study, the Ethics Committee of The Second Hospital of Dalian Medical University approved the experimental protocols, including waiving the requirement for obtaining informed consent. We confirm that all…

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  • Drivers and benefits of natural regeneration in tropical forests

    Drivers and benefits of natural regeneration in tropical forests

  • Chazdon, R. L. et al. Carbon sequestration potential of second-growth forest regeneration in the Latin American tropics. Sci. Adv. 2, e1501639 (2016).

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  • Rasmussen, L. V. et al….

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  • Regulatory effects of Poria cocos polysaccharides on gut microbiota and metabolites: evaluation of prebiotic potential

    Regulatory effects of Poria cocos polysaccharides on gut microbiota and metabolites: evaluation of prebiotic potential

    Changes in pH and SCFAs

    The pH changes observed during in vitro fermentation generally reflect the degree of microbial degradation and utilization of dietary polysaccharides. The pH changes during the fermentation of FL are shown in Fig. 1A. The…

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  • Correction: Hypoxia induced cellular and exosomal RPPH1 promotes breast cancer angiogenesis and metastasis through stabilizing the IGF2BP2/FGFR2 axis

    Correction: Hypoxia induced cellular and exosomal RPPH1 promotes breast cancer angiogenesis and metastasis through stabilizing the IGF2BP2/FGFR2 axis

  • State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China

    Wentao Ning, Jingyan Yang, Manqi Zhang, Fangfang…

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  • Unifying the analysis of bottom-up proteomics data with CHIMERYS

    Unifying the analysis of bottom-up proteomics data with CHIMERYS

    Brief description of the CHIMERYS algorithm

    Setup

    The CHIMERYS workflow is a cloud-native web service with an application programming interface, orchestrated by Kubernetes on Amazon Web Services or on-premise. The environment consists of two major…

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  • The building blocks of embryo models: embryonic and extraembryonic stem cells

    The building blocks of embryo models: embryonic and extraembryonic stem cells

  • Zhai, J., Xiao, Z., Wang, Y. & Wang, H. Human embryonic development: from peri-implantation to gastrulation. Trends Cell Biol. 32, 18–29 (2022).

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  • Zhang,…

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