Diets high in fat and sugar impair spatial navigation, found a recent study published in the International Journey of Obesity.
The Western diet is rich in saturated fats and refined carbohydrates. It has been…
Category: 5. Biology
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Insomnia and Sleep Meds Increase Disability Risk in Seniors
More symptoms of insomnia and greater use of sleep medication are linked to a higher risk of disability a year later in older adults. The corresponding study was published in Sleep.
Evidence suggests that up…
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Nature Improves Mild to Moderate Mental Health Problems
A nature-based program improved mood and anxiety levels among patients with mild to moderate mental health conditions, reported a new study published in Health & Social Care in the Community.Social…
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More Americans are using psilocybin — especially those with mental health conditions, study shows
Use of psilocybin, the hallucinogenic chemical found in what is known as “magic mushrooms,” has increased significantly nationwide since 2019, according to a new study led by researchers at the University of Colorado Anschutz Medical Campus and…
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Discovery solves 67-year-old biochemical mystery about vitamin B1
Chemists have confirmed a 67-year-old theory about vitamin B1 by stabilizing a reactive molecule in water – a feat long thought impossible. The discovery not only solves a biochemical mystery, but also opens the door to greener,…
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Scientists Discover New Phase of the Immune Response
T-cell activation involves two phases, enabling a more precise immune response. This insight may boost cancer immunotherapy effectiveness. A research team led by Wolfgang Kastenmüller and Georg Gasteiger used advanced microscopy techniques to…
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Safety profile of sikamat virus and its oncolytic potential in leukemic cells and cancer stem cells
Cell viability assays
Cancer cells and virus culture maintenance
Vero (ATCC CCL81), THP-1 (ATCC TIB-202), and K562 (ATCC CCL-243) cells were cultured in Dulbecco’s Modified Eagle Medium (DMEM), Roswell Park Memorial Institute (RPMI) 1640 Medium,…
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IL-10 targets IRF transcription factors to suppress IFN and inflammatory response genes by epigenetic mechanisms
Murray, P. J. The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription. Proc. Natl Acad. Sci. USA 102, 8686–8691 (2005).
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Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria
Nitroxoline has a broad activity spectrum against Gram-negative bacteria
Although nitroxoline (Fig. 1a) has been used for decades against uncomplicated UTIs and has a good safety profile1,4,5,6, minimum inhibitory concentration (MIC)…
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Comparative evaluation of in-house ELISA and two commercial serological assays for the detection of antibodies against SARS-CoV-2
The main goal of this study was to compare the performance of in-house ELISA with two established serological assays for detecting SARS-CoV-2 antibodies, LFA, and CLIA, using large (n = 1441) serum samples crossectionally collected from…
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