Ethical statement
All experiments involving mice were approved by Jiangxi Cancer Hospital (2024ky058).
Public data download
OS-related scRNA-seq data GSE162454 and transcriptome RNA sequencing (RNA-seq) data GSE154540, GSE39055 were obtained from…
Category: 5. Biology
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Regulatory B cells attenuate sepsis-associated pancreatic injury by regulating T cell homeostasis
Mice and treatment
Male C57BL/6 mice weighing 23–26 g (8–10 weeks of age) were purchased from animal experiment center of Xiangya Medical College (Changsha, China). All the experiments adhered strictly to the ARRIVE guidelines for the Care…
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YTHDC2 manipulates anti-tumoral macrophage polarization and predicts favorable outcomes in triple negative breast cancer
Sample collection and processing
A total of 19 TNBC patients (mean [SD] age, 45 [9] years) were included and the biopsied tumor samples were subjected to scRNA-seq (P01, P02, P03) along with the data referenced from the GSE169246 dataset27 of Gene…
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Prognostic molecular subtype reveals the heterogeneity of tumor immune microenvironment in gastric cancer
Smyth, E. C., Nilsson, M., Grabsch, H. I., van Grieken, N. C. & Lordick, F. Gastric cancer. Lancet 396 (10251), 635–648 (2020).
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Green, P. H., O’Toole,…
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![Preclinical and clinical evaluation of [64Cu]Cu-PSMA-Q PET/CT for prostate cancer detection and its comparison with [18F]FDG imaging](https://scienewsd.appsfornexus.com/wp-content/uploads/2025/04/41598_2025_98757_Fig1_HTML.png)
Preclinical and clinical evaluation of [64Cu]Cu-PSMA-Q PET/CT for prostate cancer detection and its comparison with [18F]FDG imaging
Cell lines and animals
Human prostate cancer cell line LNCaP C4-2B was obtained from the National Institutes for Food and Drug Control, while the PC-3 cell line was provided by KYINNO Biotechnology (Beijing) Co., Ltd. Balb/c mice (6–8 weeks…
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The overwintering situation and influencing factors of Fulmekiola serrata in Yunnan sugarcane planting areas of China
Sugarcane thrips, Fulmekiola serrata (Kobus) (Thysanoptera: Terebrantia), is a common leaf pest on sugarcane1,2. F. serrata is native to eastern Asia and was first described in sugarcane in Java, and has spread to Africa, North America, and South…
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Trade-offs between machine learning and deep learning for mental illness detection on social media
This section outlines the methodological framework of our study, covering data collection, preprocessing, model construction, and evaluation metrics. All experiments were conducted using Python 3. We leveraged key libraries such as pandas for…
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Domain coupling in activation of a family C GPCR
LBD closure is incompletely coupled to LBD reorientation
We performed smFRET measurements in mGluR2 using amber codon suppression to incorporate unnatural amino acids for dye addition via click chemistry (Fig. 1a). To monitor clamshell closure, we…
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Correction: Utilizing TP53 hotspot mutations as effective predictors of gemcitabine treatment outcome in non-small-cell lung cancer
Correction to: Cell Death Discovery https://doi.org/10.1038/s41420-025-02300-7, published online 27 January 2025
In this article, the order of affiliations and numbering assigned to the authors was…
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