Performance of different machine-learning (ML) classifiers and data set training
To develop an optimal ML model for differentiating anti-FtsZ compounds from non-inhibitory compounds, we built classification model using ML techniques. The…
Category: 5. Biology
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Investigation of sestrin-2 levels and thiol-disulfide homeostasis in polyp tissue of patients with nasal polyps
Although the causes of nasal polyposis are multifactorial, inflammation is one of the most important factors in the development of NP. The presence of inflammatory cells such as eosinophils, neutrophils, lymphocytes, and macrophages indicates the…
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Biochemical implementation of acceleration sensing and PIDA control
We now encourage the reader to review the first two sections of “Methods”, which outline key (mathematical and biochemical) concepts, in order to facilitate a more comprehensive understanding of the research findings presented below.
Speed and…
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From bench to bedside: the future of stable lentiviral packaging cell lines in gene therapy
Awasthi R, Maier HJ, Zhang J, Lim S. Kymriah®(tisagenlecleucel)–An overview of the clinical development journey of the first approved CAR-T therapy. Hum Vaccines Immunother. 2023;19:2210046.
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Investigations into cyanobacterial photoacclimation processes address longstanding proposals for improving crop yields
Zhu, X.-G., Long, S. P. & Ort, D. R. Improving photosynthetic efficiency for greater yield. Annu. Rev. Plant Biol. 61, 235–261 (2010).
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Anten, N. P. R….
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Toward based on concentrated multi-scale linear attention real-time UAV tracking using joint natural language specification
Wang, R. et al. Unified transformer with isomorphic branches for natural language tracking. IEEE Trans. Circuits Syst. Video Technol. 33, 4529–4541 (2023).
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Wen, S., Gong, S.,…
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Comprehensive identification of dysregulated extracellular matrix molecules in the corneal endothelium of patients with Fuchs endothelial corneal dystrophy
Ethics statement
All corneal tissues in this study were handled in accordance with the Declaration of Helsinki ethical guidelines. The RNA sequencing analyses were approved by the Ethical Review Committee at Friedrich-Alexander Universität…
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p53 protein degradation redefines the initiation mechanisms and drives transitional mutations in colorectal cancer
URI is overexpressed in APC-loss driven human CRC, correlating with poor prognosis
Searching for initiation factors driving WNT activation-based CRC, the oncogenic protein URI emerged as a compelling target that could have an impact in CRC…
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A neurally constrained computational model of context-dependent fear extinction recall and relapse
This section provides a comprehensive analysis of ConFER’s contributions to understanding fear extinction and relapse, while situating the model within broader theoretical and clinical contexts. We begin by examining how ConFER integrates with…
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Identification of genomic variants associated with colorectal cancer heredity in indigenous populations of the Amazon
Considering the limited studies involving indigenous populations, the high global incidence of colorectal cancer (CRC), and the need to assess the susceptibility of the studied population to hereditary forms of the disease, our research…
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