Despite the emergence of neoadjuvant immunotherapies, the surgical removal of a primary tumour often remains the first treatment a patient with cancer will undergo. Image-guided surgery uses real-time images to allow surgeons to see the…
Category: 5. Biology
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Structural basis for regulation of CELSR1 by a compact module in its extracellular region
Hamann, J. et al. International union of basic and clinical pharmacology. XCIV. adhesion G protein-coupled receptors. Pharmacol. Rev. 67, 338–367 (2015).
Google…
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Comprehensive comparison of the third-generation sequencing tools for bacterial 6mA profiling
Benchmarking strategy for 6mA detection in bacteria
In this study, SMRT and seven tools currently available for bacterial DNA 6mA detection using Nanopore sequencing data were gathered for benchmarking (Fig. 1b). Five of the Nanopore tools…
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Can We Program Life? Rewriting the Rulebook on How Cells Self-Organize
Non-reciprocal interactions between particles enable the regulation of dynamic states. Most systems, whether companies, societies, or entire nations, tend to function most effectively when each member performs their designated role. This…
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1.3-Million-Year-Old Mammoth DNA Rewrites Evolutionary History
The study tracks mammoth evolution over a million years using mitogenomes, showing shifts in diversity and lineage tied to Pleistocene demographic events. A recent genomic study has revealed previously unknown genetic diversity in mammoth…
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Cell-free RNA blood test identifies early-stage cancers, monitors treatment resistance and detects tissue damage
Platelet and non-haematopoietic transcripts are enriched in cfRNA. Credit: Nature (2025). DOI: 10.1038/s41586-025-08834-1
Stanford Medicine…
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New Drug Candidates for COVID & Other Viral Infections
The SARS-CoV-2 virus that causes COVID-19 emerged to sicken or kill millions of people, and it spurred a massive scientific effort to learn more about how to diagnose, treat, and prevent the disease. After…
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Giant kangaroos perished during ‘climate upheaval’
Cross sections of megafauna enamel. Samples QML1311H-WIGL8543 to QML1312-WIGL8554. Strontium transects can be identified by a series of large depressions running along the… Continue Reading
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Renewable energy forecasting using optimized quantum temporal model based on Ninja optimization algorithm
Bali Swain, R., Karimu, A. & Gråd, E. Sustainable development, renewable energy transformation and employment impact in the eu. Int. J. Sustain. Dev. World Ecol. 29, 695–708. https://doi.org/10.1080/13504509.2022.2078902 (2022).
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An engineered human placental organoid microphysiological system in a vascular niche to model viral infection
Design and operation of the placental organoid MPS
Human placenta development in vivo is a dynamic and complex process, relying on the coordinated control of inherent cues and the extracellular environment, such as the matrix, multiple cell types,…
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