Cell culture
Bladder cancer cell lines and control urothelial cells were cultured in high-glucose Dulbecco’s modified Eagle’s medium (DMEM) or RPMI 1640 medium supplemented with 10% fetal bovine serum (FBS) and 1% penicillin‒streptomycin….
Category: 5. Biology
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the unusual mathematics that gives rose petals their shape
As rose petals grow, they curl outwards and form pointed corners. The pattern is related to extrinsic, rather than intrinsic, geometry.Credit: bibi57/Getty
The growth of rose petals exploits a geometric trick previously unobserved in nature,…
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AI carves out a niche in ecology and conservation research
Tuia, D. et al. Nat. Commun. 13, 792 (2022).
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Gadot, T. et al. IET Comput. Vis. 18, 1193–1208 (2024).
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Progressive accumulation of circulating CD27−CD28− effector/memory CD8+ T cells in patients with lung cancer blunts responses to immune checkpoint inhibitor therapy
Patients with lung cancer exhibit a stage-dependent progressive alteration in the composition of peripheral blood CD8+ T cell populations
To investigate whether tumors induce alterations in the composition of peripheral blood CD8+ T cells, we…
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DOT cells for colorectal cancer immunotherapy
World Health Organization. https://go.nature.com/3EarPTD (11 July 2023).
Lin, K. X. et al. Cancer Immunol. Immunother. 72, 3875–3893 (2023).
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Microglia-driven inflammation induces progressive tauopathies and synucleinopathies
Microglia-driven inflammation induces progressive tauopathies and synucleinopathies
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Fishing for covalent peptides | Nature Chemical Biology
Scott, D. E., Bayly, A. R., Abell, C. & Skidmore, J. Nat. Rev. Drug Discov. 15, 533–550 (2016).
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Boike, L., Henning, N. J. & Nomura, D. K. Nat. Rev. Drug…
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Discovery of novel DdlA inhibitors in multidrug-resistant Pseudomonas aeruginosa using virtual screening, molecular docking, and dynamics simulations
Retrieval and preparation of DdlA structure
This study aimed to identify potential inhibitors of the d-alanine–d-alanine ligase (DdlA) isoform in P. aeruginosa. The DdlA structure was retrieved from the Protein Data Bank (PDB ID: 8EVV). This…
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Powerful protein editors offer new ways of probing living cells
Protein molecules (artist’s illustration) fold into their final shapes. Newly developed editors can swap out bits of a protein for other molecules and amino acids.Credit: Ruslanas Baranauskas/Science Photo Library
A powerful technique that…
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Cracking the Code for Tastier Apples: New Genome Study Reveals Secrets
New genomic analysis findings could help inform breeding efforts for apples that are tastier and more resilient. A comprehensive new study comparing the genomes of species within the Malus genus, including the domesticated apple and its wild…
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