Category: 5. Biology

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  • Palmitoylation regulates ferroptosis and anti-tumor immunity

    Palmitoylation regulates ferroptosis and anti-tumor immunity

    Palmitoylation regulates ferroptosis and anti-tumor immunity

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  • The role of gut microbiota on skeletal muscle strength in LDLR knockdown aging mice

    The role of gut microbiota on skeletal muscle strength in LDLR knockdown aging mice

    Identification of specific skeletal muscle LDLR knockdown mouse models

    At the level of protein, the content of LDLR of the Ocon group was increased compared with the Acon (Fig. 1A, B). In addition, the content of LDLR in the OLKd group was lower…

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  • Exploring prokaryotic diversity in permafrost-affected soils of Ladakh’s Changthang region and its geochemical drivers

    Exploring prokaryotic diversity in permafrost-affected soils of Ladakh’s Changthang region and its geochemical drivers

  • Van Everdingen, R. O. (ed) Multi-language Glossary of Permafrost and Related ground-ice Terms in Chinese, English, French, German, Icelandic, Italian, Norwegian, Polish, Romanian, Russian, Spanish, and Swedish (International Permafrost…

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  • CD56 expression modulates NAD+ metabolic landscape and predicts sensitivity to anti-CD38 therapies in multiple myeloma

    CD56 expression modulates NAD+ metabolic landscape and predicts sensitivity to anti-CD38 therapies in multiple myeloma

    In multiple myeloma (MM), monoclonal antibodies targeting CD38, such as Daratumumab (Dara) and Isatuximab (Isa), are standard-of-care drugs that produce good responses. However, it is likely that some…

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  • Profiling 92 circulating neurobiological proteins identifies novel candidate biomarkers of long-term cognitive outcome after ischemic stroke

    Profiling 92 circulating neurobiological proteins identifies novel candidate biomarkers of long-term cognitive outcome after ischemic stroke

    Study population and baseline characteristics

    This study sample comprises of 205 cases from a sub-study within the longitudinal observational cohort study Sahlgrenska Academy Study on Ischemic Stroke (SAHLSIS) with available blood samples from all…

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  • De novo non-canonical nanopore basecalling enables private communication using heavily-modified DNA data at single-molecule level

    De novo non-canonical nanopore basecalling enables private communication using heavily-modified DNA data at single-molecule level

  • Goldman, N. et al. Towards practical, high-capacity, low-maintenance information storage in synthesized DNA. Nature 494, 77–80 (2013).

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  • Planting date affects biochemical characteristics, assimilate remobilization, and yield of safflower under water stress

    Planting date affects biochemical characteristics, assimilate remobilization, and yield of safflower under water stress

    Field experiment and treatments

    The field plots were located at the College of Agriculture and Natural Resources of Darab (28° 45.0′ N, 54° 26.8′ E), Fars province, Iran during 2018 and 2019 growing seasons. Before initiation of the…

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  • Cytosolic NADK is conditionally essential for folate-dependent nucleotide synthesis

    Cytosolic NADK is conditionally essential for folate-dependent nucleotide synthesis

  • Rancati, G., Moffat, J., Typas, A. & Pavelka, N. Emerging and evolving concepts in gene essentiality. Nat. Rev. Genet. 19, 34–49 (2017).

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  • Shalem, O. et al….

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