Inherited traits from paternal cardiac lesions result in adapted response to cardiac injury in offspring
Category: 5. Biology
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Inherited traits from paternal cardiac lesions result in adapted response to cardiac injury in offspring
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Chromatin loops are an ancestral hallmark of the animal regulatory genome
Cell and animal cultures, sample preparation and crosslinking
S. arctica coenocytic culture was grown in marine broth (Difco, 3704 g l−1) at 12 °C in 25 cm2 flasks. Cells were passaged every 7 days using a 1:100 dilution. To…
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Getting anxious about immune system activation
Immune system activation can result in persistent mood changes, exemplified by the increased incidence of anxiety and depression in people with immune disorders such as psoriasis, but the neural mechanisms that underlie immune system-mediated…
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Improved maximum growth rate prediction from microbial genomes by integrating phylogenetic information
A phylogenetically informed model for maximum growth rate prediction
We compiled a dataset of 633 species with recorded doubling times from the Madin et al. trait database9. However, 85 species were excluded due to unidentifiable species names in…
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Long-term multi-meta-omics resolves the ecophysiological controls of seasonal N2O emissions during wastewater treatment
IPCC Climate Change 2014: Synthesis Report (eds Core Writing Team, Pachauri, R. K. & Meyer L. A.) (IPCC, 2014).
Tian, H. et al. A comprehensive quantification of global nitrous oxide sources and sinks. Nature 586, 248–256 (2020).
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An uneasy truce between population health and the gene pools within our bodies
De novo mutations frequently arise in all cell types of the human body. Such mutations occur in somatic cells during development — when a single-cell zygote replicates and divides into 37 trillion different cells — or as the body ages,…
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Detailed mouse brain map created with off-the-shelf microscope
Researchers used an AI model to reconstruct neural circuits in brain samples imaged using a light microscope.
Scientists have found a way to map the intricate patterns of cells in mouse brain tissue with an off-the-shelf light microscope, using a…
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A promising approach to diabetic osteoporosis: oxymatrine’s effects on gut microbiota and osteoblasts
Animal models and experimental procedure
A total of 50 Sprague-Dawley rats, which were healthy males weighing 200 ± 20 g, were obtained from the Zhejiang Academy of Traditional Chinese Medicine. The protocols used in animal experiments were…
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Autonomic physiological coupling of the global fMRI signal
Yackle, K. et al. Breathing control center neurons that promote arousal in mice. Science 355, 1411–1415 (2017).
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Anaclet, C. & Fuller,…
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Understanding the logic and grammar of cis-regulatory elements
Cis-regulatory elements (CREs), such as promoters and enhancers, possess complex architectures of transcription factors that determine specific expression patterns, levels and responses to diverse cellular or environmental cues. Understanding the…
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