Poorter, L. et al. Biodiversity and climate determine the functioning of Neotropical forests. Global Ecol. Biogeogr. 26, 1423–1434 (2017).
Tariq, A. et al. Plant root mechanisms and their…
Category: 5. Biology
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MCL-1 as a molecular switch between myofibroblastic and pro-angiogenic features of breast cancer-associated fibroblasts
Cell culture and reagents
Fresh human mammary samples were obtained from treatment-naive patients with invasive carcinoma after surgical resection at the Institut de Cancérologie de l’Ouest, Nantes/Angers, France. As required by the French…
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What 1,500-Year-Old Poo Reveals About Vanishing Species
Ancient kākāpō droppings have revealed a startling truth: more than 80% of the bird’s parasites have disappeared. This “coextinction” shows that as endangered animals struggle to survive, their microscopic companions often vanish first….
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Scientists Discover “Master Key” Protein for Stronger Memory and Learning
Research led by Rutgers suggests there could be significant new possibilities for treating neurodegenerative diseases and brain injuries. Researchers have uncovered how a specific protein supports the stability of connections between brain cells,…
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Squashing the spotted lanternfly problem may require enlisting other species
A beautiful menace is on the move in the United States. Polka-dotted, red-and-gray-winged insects are gliding along sidewalks, climbing on plants and crawling up buildings. Spotted youngsters are leaping away to avoid a sticky end at…
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Revolutionizing therapeutic protein design with synthetic biology
In medicine and biotechnology, the ability to evolve proteins with new or improved functions is crucial, but current methods are often slow and laborious. Now, Scripps Research scientists have developed a synthetic biology platform…
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RNA sequencing reveals molecular drivers for better regenerative therapies
Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular drivers of cellular differentiation…
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CRISPR screening uncovers microproteins involved in fat storage
The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide. This prevalent condition is also linked to other metabolic disorders, including type 2 diabetes, cardiovascular diseases,…
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Researchers uncover dozens of traits driven by maternal versus paternal genes
By tracing maternal and paternal inheritance without parental DNA, scientists have mapped dozens of parent-specific genetic effects, uncovering how the same variant can drive or protect against disease depending on which parent it…
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Structure and function of the human apoptotic scramblase Xkr4
Full length hXkr4 scrambles lipids
To test whether Xkr proteins are scramblases we sought to purify and functionally reconstitute them in proteoliposomes. A screen of GFP-tagged family members using fluorescence size exclusion chromatography…
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