MicroRNAs, whose discovery was recognized with the 2025 Nobel Prize in Physiology or Medicine, are central regulators of gene expression, yet a fundamental question has remained unanswered: how cells choose between the two strands produced from…
Category: 5. Biology
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Decoded rules of microRNA strand selection reveal conserved, programmable features
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Baby chimpanzees like to free fall through trees
Given the many similarities between humans and chimpanzees, one might assume…
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Horses can smell human fear when we sweat
Horses can smell your fear. If you are experiencing this emotion while standing near a horse, they will be able to detect it through your scent alone, which changes their behavior and physiology. That’s the conclusion of a new study published in…
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Sniffing out cancer: Trained dogs can detect hemangiosarcoma by scent
Cancer is a leading cause of death in both humans and pets; studies suggest that between one-third and one-half of all dogs will develop cancer during their lifetime.
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Mobile app forecasts future vineyard climates to help winegrowers adapt to change
What will the climate of a given region be like in 20, 30 or 50 years? Climate analogs provide a robust methodological framework to address this question by identifying regions whose current climate matches the future climate of another area.
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Scientists are rethinking bamboo as a powerful new superfood
The first-ever academic review focused on bamboo as a food has uncovered a wide range of possible health benefits. Researchers found evidence suggesting bamboo consumption may help regulate blood sugar, reduce inflammation, support digestive…
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Aesculetin (6,7-dihydroxycoumarin) enhances the differentiation of human bone marrow-derived mesenchymal stem cells into functional hepatocyte-like cells
So, B. N. & Reddy, K. R. Liver transplantation for the nonhepatologist. Med. Clin. North. Am. 107, 605â621. https://doi.org/10.1016/j.mcna.2023.01.004 (2023).
Lai, J. C. et al. Development of…
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CDC25C downregulation suppresses HCC growth via mitochondrial stress-induced autophagy and apoptosis
Tong, H. et al. MACC1-AS1 promotes hepatocellular carcinoma cell invasion and proliferation by regulating PAX8. Aging (Albany NY). 12, 70â79. https://doi.org/10.18632/aging.102585 (2020).
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Host-derived interleukin-1α drives tumor immunosuppression by reprogramming tumor-associated myeloid cells
Olingy, C. E., Dinh, H. Q. & Hedrick, C. C. Monocyte heterogeneity and functions in cancer. J. Leukoc. Biol. 106, 309â322 (2019).
Veglia, F., Sanseviero, E. & Gabrilovich, D. I….
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Af-CUT&Tag: a sensitive and antibody-free chromatin profiling method using genetically encoded tags and high-affinity binders fused to Tn5
Nakato, R. & Sakata, T. Methods for ChIP-seq analysis: a practical workflow and advanced applications. Methods 187, 44â53 (2021).
Park, P. J. ChIP-seq: advantages and challenges of a maturing…
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