Category: 5. Biology

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  • Astrocytic noncanonical WNT5B signaling modulates extracellular matrix remodeling and neuropathology in Huntington’s disease

    Astrocytic noncanonical WNT5B signaling modulates extracellular matrix remodeling and neuropathology in Huntington’s disease

    Human brain samples

    Neuropathological examination of normal and HD postmortem brain samples followed established protocols from the Boston University Alzheimer’s Disease Research Center (BU ADRC). Striatal histopathology was confirmed and graded…

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  • Modeling tissue-specific Drosophila metabolism identifies high sugar diet-induced metabolic dysregulation in muscle at reaction and pathway levels

  • Droujinine, I. A. & Perrimon, N. Interorgan communication pathways in physiology: focus on Drosophila. Annu. Rev. Genet. 50, 539–570 (2016).

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  • Priest, C. & Tontonoz, P. Inter-organ cross-talk…

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  • The AHCY–adenosine complex rewires mRNA methylation to enhance fatty acid biosynthesis and tumorigenesis

    The AHCY–adenosine complex rewires mRNA methylation to enhance fatty acid biosynthesis and tumorigenesis

    Cell culture

    HEK293T human embryonic kidney cells, the human lung cancer cell lines A549 and H1299, the human liver cancer cell line HepG2, and the human breast cancer cell line MCF7 were cultured in DMEM supplemented with 10% fetal bovine serum…

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  • On the use and misuse of pangenome and related terms

    On the use and misuse of pangenome and related terms

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  • The rise of spatial insights into tumour tissue architecture

    Novel technologies in biology often trigger an initial surge of newly generated data. Over time, as these technologies advance, the rate of data creation begins to outpace the ability to analyse and interpret it. Interpretation follows a…

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  • One year of Nature Reviews Biodiversity

    Our team reflects on a successful first year and discusses our continued aspiration to be an outlet for effective syntheses of essential advances in biodiversity science and policy.

    This month, Nature…

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  • Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors

    Expanding the toolbox to develop IAP-based degraders of TEAD transcription factors

  • Lin, K. C., Park, H. W. & Guan, K.-L. Deregulation and therapeutic potential of the Hippo pathway in cancer. Annu. Rev. Cancer Biol. 2, 59–79 (2018).

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  • Holden, J. & Cunningham, C. Targeting the…

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  • ACE2 expression by colonic epithelial cells is associated with viral infection, immunity, and energy metabolism

  • Porcari, S. et al. Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: Systematic review and meta-analysis. Gut 73(9), 1431–1440 (2024).

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  • Mehta, D. et…

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  • First evidence of naturally vertically transmitted Coxiella-like endosymbionts in Haemaphysalis Bispinosa from dairy cattle in Indonesia

  • Petney, N. T et al. Ticks (Argasidae, Ixodidae) and tick-borne diseases of continental Southeast Asia. Zootaxa 4558, 1–89 (2019).

  • Guglielmone, A. A., Nava, S. & Robbins, R. G. Geographic distribution of the hard ticks (Acari: ixodida: Ixodidae)…

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