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Thomas, M. C. & Chiang, C. M. The general transcription…
Category: 5. Biology
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Glycolytic heterogeneity drives metabolic-targeted therapy in pancreatic ductal adenocarcinoma
Single-cell RNA sequencing analysis
Preprocessing and clustering methods
The scRNA-seq dataset used for downstream analysis included 24 PDAC and 11 normal pancreas samples from ref. 23 and 23 PDAC and 5 normal pancreas samples from ref. 24. Data…
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Author Correction: Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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C1q-dependent clearance of alpha-synuclein allows macrophages to transiently limit enteric synucleinopathy in male mice
Beach, T. G. et al. Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders. Acta Neuropathol. 119, 689–702 (2010).
Rao, M. & Gershon,…
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From in-silico QSAR modeling to in-vitro MTT assay: experimental validation of novel uPAR leads for triple-negative breast cancer (TNBC) and skin cancer
Siegel, R. L., Giaquinto, A. N., Jemal, A. & Cancer statistics, 2024. CA: A Cancer Journal for Clinicians 74, 12–49, https://doi.org/10.3322/caac.21820 (2024).
Guan, X. Cancer metastases: challenges and opportunities. Acta Pharm. Sinica B. 5,…
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Carbon Dots and mesoporous silica nanocomposites improve spray-induced gene silencing to suppress plant RNA and DNA viruses
Savary, S. et al. The global burden of pathogens and pests on major food crops. Nat. Ecol. Evol. 3, 430–439 (2019).
Velasco, L., Ruiz, L., Galipienso, L., Rubio, L. & Janssen, D. A….
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Cereblon induces G3BP2 neosubstrate degradation using molecular surface mimicry
Cell treatment for global proteomics experiments
CAL-51 cells were cultured in DMEM (Gibco) supplemented with 10% FBS (Corning). For global proteomics profiling experiments, 12-well plates of subconfluent 70–90% CAL51 cells were incubated for…
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Functional and structural insights into interactions between β-Arrestin 1 and Gαs or Gαi1
Shukla, A. K., Xiao, K. & Lefkowitz, R. J. Emerging paradigms of beta-arrestin-dependent seven transmembrane receptor signaling. Trends Biochem. Sci. 36, 457–469 (2011).
Hilger, D., Masureel,…
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In silico design and immunoinformatics assessment of a multiepitope vaccine targeting borealpox virus
Omoruyi, P. O. et al. Borealpox virus: A comprehensive review of its emergence and global recommendations. J. Health Sci. Med. Res. 43(2), 20241092 (2025).
Bishnoi, A. et al. Understanding…
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Beyond neurons: astrocytic ensembles stabilize memories after recall
In a recent study published in Nature, Dewa et al. showed that emotionally salient experiences “biologically tag” small ensembles of astrocytes, creating multiday traces that can be reactivated…
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