Category: 5. Biology

Mosses may appear simple, but they’re far from fragile. They thrive in some of the harshest places on Earth — Antarctica, arid deserts, high mountain peaks and more.

“We’ve long wondered about the molecular mechanisms that…

If you step on a snail, you’ll know it. The crunch of its shell or the feel of…

A snail may hold the key to restoring vision for people with some eye diseases.

Golden apple snails (Pomacea canaliculata) are freshwater snails from South America. Alice Accorsi became familiar with the species as a graduate student…

Lactic acid (LA) has transitioned from being perceived as a mere glycolytic waste product to a pivotal regulator of tumor-immune crosstalk. Historical milestones—from Scheele’s 1780 isolation from sour milk to Zhao’s 2019…

It’s known as biology’s central dogma: All living organisms’ genetic information is stored in DNA, which is transcribed into RNA, which is translated into proteins that perform nearly all essential tasks in a cell. A tiny…

A new study from researchers at the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) reveals that extremely simple peptides can mimic a biological process that protects sensitive proteins from environmental…

For cancer- and infection-fighting T cells, glucose offers far more than a simple sugar rush.

A new discovery by Van Andel Institute scientists reveals that glucose, an essential cellular fuel that powers immune cells, also aids in…

A new study finds that kids with obesity are more likely to have obese parents because they inherit obesity-related genes, and to a smaller extent, are impacted indirectly by genes carried by the mother – even when those genes…

Domain closure of D2HDH on substrate binding

The structure of the non-productive ternary complex of D2HDH with both oxidised NADP⁺ and 2-ketohexanoic acid was determined at 1.26 Å resolution, using crystals grown from protein prepared in 1 M…

In silico analysis to identify new CD36 inhibitors

To identify new CD36 inhibitors, we screened in silico a commercial library of 30,000 compounds (https://www.hit2lead.com) targeting a protein region around the FA binding site centered at Val142…