Staunton, J. & Wilkinson, B. Biosynthesis of erythromycin and rapamycin. Chem. Rev. 97, 2611–2629 (1997).
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Floss, H. G. & Yu, T. W. Rifamycin – mode of action,…
Category: 5. Biology
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Ancient allopolyploidy and specific subgenomic evolution drove the radiation of poplars and willows
Leebens-Mack, J. H. et al. One thousand plant transcriptomes and the phylogenomics of green plants. Nature 574, 679–685 (2019).
Jiao, Y. et al. Phylogenomic analysis reveals ancient genome…
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Scientists open new atlas of genetic diversity with advanced sequencing
A landmark study harnesses long-read sequencing to reveal vast, previously undetected structural variations in human DNA, reshaping our understanding of genetics and disease potential.
Study: Structural variation in 1,019…
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Warming Climate Sparks Innovative Wildlife Protection Measures in Guatemala
Scientists with the Wildlife Conservation Society have documented a remarkable diversity of wildlife visiting the artificial watering holes in Guatemala’s Maya Forest.
Jaguars get relief from the heat at an artificial waterhole in Guatemala….
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Analytical Ultracentrifugation (AUC) for Characterization of Lipid Nanoparticles (LNPs): A Comprehensive Review
Lipid nanoparticles (LNPs) and liposomes (Figure 1) have revolutionized the medical field by serving as carriers for a wide range of therapeutic molecules,
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Blocking nutrient scavenging weakens pancreatic tumor defenses
Cancer cells and tumors do not exist in a vacuum. Far from the isolation and self-sufficiency of the fictional Wakanda, tumors develop in and alter the nearby milieu of immune cells, connective tissue, blood vessels and a sea of…
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IRF-5 identified as key to preventing immune cell exhaustion
In fighting chronic infections or certain cancers, CD8+ T cells-the immune system’s frontline soldiers-eventually become exhausted. They lose effectiveness and respond less efficiently to threats. This weakening is a major…
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New redox-sensitive pathway reveals how cells activate AMPK in response to metabolic stress
AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress. While upstream activation by the kinase LKB1 is well recognized, the precise mechanism by which LKB1 is…
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This 500-Million-Year-Old Sea Creature Had a Brain Like a Spider
An exquisitely preserved fossil from half a billion years ago has turned our understanding of spider evolution upside down. Scientists studying the fossilized brain of Mollisonia symmetrica, a marine creature from the Cambrian period, have found…
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Your DNA Is Full of Ancient Viruses – And They’re Running the Show
For years, scientists thought certain parts of our DNA were useless—leftovers from ancient viruses that served no purpose. But a new international study has flipped that idea on its head. Researchers have discovered that these so-called…
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