Chloroquine’s access to the cavity recapitulates expected PfCRT isoform relationships
The CQ-sensitive wild-type (3D7) parasites are unable to evade the toxic effects of CQ because 3D7-PfCRT is unable to transport the drug in sufficient amounts…
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Exploring the polygenic landscape of wool traits in Turkish Merinos through multi-locus GWAS approaches: middle Anatolian Merino
The data on FD and SL reveal different patterns of heritability and variability. FD shows moderately high heritability (h2 = 0.461) but low variability (CV = 7.570%), suggesting that while genetic factors significantly influence this…
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Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice
Van Opijnen, T., Bodi, K. L. & Camilli, A. Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms. Nat. Methods 6, 767–772 (2009).
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Early antiviral type I interferon impairs lung metastasis
Invasive breast cancer is a leading cause of cancer-related death among women. Metastatic spread of breast cancer to the lungs is common and is associated with markedly decreased lifespan. The immunosuppressive environment of cancer can increase…
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Author Correction: Structural basis of Nipah virus RNA synthesis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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Sweet success in CAR T cells
The effector function of T cells is heavily dependent on glycolysis, however the tumour microenvironment (TME) is often glucose-deficient. Noting that tumour cells can generally not drive glycolytic flux using fructose and that fructose is…
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Correction: Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis
Correction: Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis
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Molecular mechanisms and therapeutic targets in glioblastoma multiforme: network and single-cell analyses
WGCNA and functional enrichment analysis of the hub genes in glioma
To investigate the correlation between gene expression and glioma progression, datasets GSE4290, GSE108476, and GSE15824 were analyzed using weighted gene co-expression network…
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Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis
Further information and requests for materials, resources and reagents should be addressed to Yinxiu Zhan or Nicola Iovino.
Fly stocks
The fly lines employed in this manuscript were raised on corn flour molasses medium (consisting of 12 g agar,…
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Effects of whole brain proton irradiation at conventional or ultra-high dose rate (FLASH), in adult male Sprague Dawley rats
Two experiments were conducted: a comprehensive behavioral and cognitive assessment (Experiment 1) and a cytokine study (Experiment 2). There were 4 groups in each experiment: Sham, CV, FLASH-60, and FLASH-95. Behavioral assessment began on PID7….
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