The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma

Phosphorylated SMAD1/5 levels in different MB tumor subgroups

We analyzed seven PDX MB samples, three SHH, two Group 3 and two Group 4 (Fig. 1). Multispectral immunofluorescence analysis showed clear and quantifiable levels of C-terminally…

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