High binding affinity between JA and KRAS G12D
In silico molecular docking analysis was conducted to predict the interactions between JA and wild-type (WT) KRAS, as well as its mutant variants (G12D, G12V, and G12C) (Fig. 2). The docking…
Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways
