Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics

IL-1 pulse duration produces a monotonic correlation between same-cell IKK and NF-κB responses

We previously developed a CRISPR-modified U2OS cell line that co-express FP fusions of NEMO (EGFP-NEMO) and RelA (mCh-RelA) from their endogenous loci….

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