P-Rex2 suppresses glucose uptake into liver and skeletal muscle through different adaptor functions

Mice

Prex2^–/– were previously described¹⁵, and were backcrossed 10 times to C57Bl6 genetic background, unless otherwise indicated. Prex2^–/– mice were compared to Prex2^+/+ mice derived on the same genetic background. To minimise genetic…