OTUD3 dysfunction in fibroblasts leads to development of colitis in the presence of dysbiotic microbiota-derived cGAMP.
OTUD3 prevents ulcerative colitis by inhibiting microbiota-mediated STING activation | Science Immunology

OTUD3 dysfunction in fibroblasts leads to development of colitis in the presence of dysbiotic microbiota-derived cGAMP.