High mtDNA content identifies oxidative phosphorylation-driven acute myeloid leukemias and represents a therapeutic vulnerability

High mtDNAc drives a more OXPHOS-like metabolic state in AML

To better understand the role of mtDNAc in a hematological context, we compared the mtDNAc between healthy and leukemic samples. mtDNAc was analyzed in BM aspirates of 482 newly…

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