Bithionol is ineffective in a mouse model of S. aureus implant-associated osteomyelitis despite potent in vitro activity

Bacterial strains, culture and antibiotics

The clinical S. aureus isolate SAU060112 was used for both in vitro and in vivo experiments. SAU060112 was originally isolated from a prosthetic knee infection²¹. S. aureus cultures were cultivated on…