Design and synthesis of a novel quinoline thiazolidinedione hybrid as a potential antidiabetic PPARγ modulator

Chemistry

The titled compound 7 was synthesized as per the route outlined in Fig. 6. Acetanilide was treated with Vilsmeier–Haack reagent (POCl3 and N,N-dimethyl formamide (DMF)) to form intermediate 1. Intermediate 1 was then treated with…

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