Gasdermin D deficiency aggravates nephrocalcinosis-related chronic kidney disease with rendering macrophages vulnerable to necroptosis

Transcriptional and histological analyses show Gsdmd expression in tubulointerstitial cells in chronic oxalate nephropathy

Gsdmd is known to be expressed in macrophages, and has a pivotal role in pyroptosis [18]. To investigate the gene expression…

Continue Reading