Selenomethionine inhibits the proliferation of hypoxia-induced pulmonary artery smooth muscle cells by inhibiting ROS and HIF-1α-ACE-AngII axis

Isolation and cell culture of PASMCs

The experimental animals used in the study were male Sprague-Dawley (SD) rats, specific pathogen free (SPF) grade, 5 weeks of age. The weight was (130 ± 10) g, which was purchased from Beijing Huafu…

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