Utility of 3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde in the synthesis of novel 1,3,4-thiadiazoles or 1,3-thiazoles and study their cytotoxic activity

Chemistry

In our research program we utilized 3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde (1)⁴⁹ as a precursor for synthesis of new heterocycles. Thus, condensation of compound 1 with benzyl or methyl hydrazinecarbodithioates 2a,…